Standard Sanitary SS Mixer

Product Overview

The standard sanitary SS mixer is the most widely deployed sanitary mixer in the ywmixing range. It is built in DN25 to DN150 main-line sizes, with the same polished SS316L housing and tri-clamp ferrule ends as the other sanitary variants, but with a wider element count range (3-8 elements) and support for both SV plate and SK helical geometries. The standard version is the workhorse of pharmaceutical, biotech, dairy, and food processing lines, and is the variant we recommend when the application is "general-purpose sanitary blending in a validated CIP/SIP loop."

The unit is rated for the standard PN16 (10 bar) sanitary pressure class and the standard EPDM gasket temperature envelope of -10°C to +130°C. The polished surface is Ra ≤ 0.8 μm mechanical as standard, with electropolish to Ra ≤ 0.4 μm available for bioprocess and gene-therapy service. The element pack is removable for cleaning and inspection, and the housing remains in the line. The mixer supports CIP at 1.5-2.5 m/s and SIP at 121-130°C, with the validation report supplied per EHEDG and 3-A requirements.

The standard sanitary mixer is the variant most commonly specified in the OEM skid packages for pharmaceutical and food processing equipment. It is the default mixer in the buffer make-up skid, the WFI distribution loop, the CIP return loop, the ingredient blending line, and the media preparation system. The DN50-DN100 sizes account for approximately 60% of the sanitary mixers we ship, and the DN25-DN150 range accounts for approximately 90%.

Design Features

The standard sanitary housing is a single SS316L forging for DN25-DN100 sizes, and a fabricated SS316L spool for DN125-DN150. The internal bore is polished to Ra ≤ 0.8 μm as standard, with no sharp corners at the ferrule-to-bore transition. The bore is straight and unobstructed except for the element pack, which is supported by machined shoulders at each end of the housing. The element pack is retained by an internal tri-clamp ring at the upstream end and a retaining shoulder at the downstream end.

The element pack is a stand-alone assembly that slides into the housing on a precision spigot. For SV plate technology, the plates are stacked with the corrugations rotated 90° to each other, captured between two end caps, and held in compression by a small disc-spring. For SK helical technology, the elements are twisted from flat bar and welded end-to-end to form a continuous helix, with the upstream end pinned to a shoulder. Either design produces a robust, cleanable element pack that can be removed in seconds.

The housing is fully drainable: the bore is straight, the element pack is centered, and there is a 1-2° slope toward the outlet in the standard installation orientation. When the line is drained, gravity pulls all residual fluid to the outlet, and the polished surface does not retain a film. The drainability is documented in the validation report per EHEDG Doc 2 and 3-A 18-03.

All wetted materials comply with FDA 21 CFR and USP Class VI. The SS316L housing is supplied with a 3.1 MTR and a ferrite content report. The EPDM gaskets are USP Class VI tested and supplied with a lot-traceable certificate. The element pack is supplied with a 3.1 MTR for the SS316L material and a surface-finish report. The mixer is passivated per ASTM A967 and delivered in a Class 100 cleanroom double-bag.

Technical Specifications

Parameter	Value
Connection Standard	Tri-clamp per ISO 2852 / DIN 32676 / ASME BPE / BS 4825-3
Pipe Diameter Range	DN25 (1") to DN150 (6")
Pressure Rating	PN16 (10 bar at 25°C) for SS316L standard
Flow Rate Range	0.5 m³/h (DN25 low) to 200 m³/h (DN150 high)
Temperature Range	-10°C to +130°C (EPDM) / -20°C to +200°C (PTFE)
Housing Material	SS316L (≤ 0.030% C, ASTM A479) — forged or fabricated
Mixing Element	SV plate (DN25-100) or SK helical (DN80-150) — SS316L
Element Count	3 to 8 elements (DN-dependent)
Surface Finish (Wetted)	Ra ≤ 0.8 μm mechanical (default) / Ra ≤ 0.4 μm electropolish
Gasket	EPDM USP Class VI (default), FKM, PTFE, Silicone
Certifications	ASME BPE, 3-A 18-03, EHEDG Doc 8, FDA, USP Class VI
Packaging	Class 100 cleanroom double-bag

Connection Options

All connections are tri-clamp, drilled to the same standard as the rest of the sanitary range. ISO 2852 is the default for European and Asian pharmaceutical plants, with ferrule sizes 1" through 6" (DN25-DN150) stocked. The ferrule OD and the clamp dimensions match the standard ISO table, so the mixer drops into the line with no special fittings.

For European pharmaceutical plants, DIN 32676 tri-clamp is also available. For North American pharmaceutical and biotech, ASME BPE tri-clamp is supplied with the BPE surface finish codes. For UK and Commonwealth pharmaceutical plants, BS 4825-3 is available. For dairy and food applications, the mixer is supplied with 3-A 18-03 certification and the standard 3-A ferrule geometry.

Weld-end sanitary connections (orbital weld stubs per ASME BPE) are available for permanent sanitary installations. The weld stubs are polished to the same Ra finish as the housing, and the orbital weld is performed in the field by a certified orbital welding operator. This is the standard for high-purity pharmaceutical water systems where the tri-clamp gasket is considered a potential contamination source.

For high-pressure service above PN16, the housing is reinforced with a thicker wall and the tri-clamp ferrules are upgraded to higher-pressure ratings. For PN25 service, the ferrules are per the high-pressure tri-clamp tables, and the clamp is a heavy-duty bolt-clamp rather than the standard pinch-clamp. For PN40 service, the mixer is built with butt-weld ends rather than tri-clamp — see the welded sanitary mixer variant for the PN25-PN40 range.

Applications

Pharmaceutical buffer and media preparation. The standard sanitary mixer is the workhorse of buffer make-up and cell-culture media preparation in upstream bioprocess. The DN50-DN100 sizes match the typical buffer make-up skid flow rates of 5-50 m³/h. The CIP/SIP compatibility is essential for the validated multi-product facility, and the polished surface prevents batch-to-batch carryover.

WFI and purified water loops. The mixer is installed in purified water and WFI distribution loops to maintain a homogeneous conductivity and to support in-line analytical measurements. The polished surface and the SIP capability are essential for the aseptic boundary. Typical size is DN25-DN80, processing 1-30 m³/h of WFI.

Dairy processing. Milk standardization, cream blending, and yogurt mix preparation use the standard sanitary mixer for in-line blending. The 3-A certification is required for the dairy regulatory regime, and the polished surface meets the EHEDG hygienic design criteria. Sizes DN25-DN100 are typical, processing 2-50 m³/h.

Beverage blending. Beer, wine, soft drink, and juice blending all use the standard sanitary mixer for in-line dosing of flavors, colors, and sweeteners. The CIP compatibility supports the brewery CIP cycle (180°C caustic), and the polished surface prevents flavor carryover between batches. Typical size is DN25-DN80, processing 2-30 m³/h.

Personal care and cosmetics. Shampoo, lotion, cream, and gel manufacture use the standard sanitary mixer for in-line blending of water-based formulations. The sanitary design matches the GMP requirements of the cosmetic industry, and the polished surface supports the validated cleaning procedures that govern multi-product lines. Typical size is DN25-DN50, processing 0.5-10 m³/h.

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